Agomelatine is the generic term for an atypical antidepressant, used to treat depression. Off-label patients buy Agomelatine to treat chronic fatigue, neuropathic pain, brain fog, improve sleep, anxiety and similar disorders, and other uses.

This product should not be used in patients under age 18, over age 75, or in patients of any age who suffer from dementia.

Depending on location patients may buy Agomelatine under its brand names of Valdoxan, Melitor, or Thymanax.

A Very Effective Treatment

Like most other antidepressants, Agomelatine increases levels of neurotransmitters that regulate mood. Unlike other antidepressants, Agomelatine also mimics melatonin, a hormone responsible for regulating the circadian rhythm. While most patients associate the circadian rhythm with sleep/wake cycles, many do not know that it is also responsible for mood, anxiety, appetite, body temperature, and other effects.

Patients---both depressed and not depressed---often have at least a few abnormal circadian rhythm functions; in patients who are depressed and/or anxious, the circadian rhythm is often severely disrupted. Those who buy Agomelatine find the medication quickly starts restoring a healthy circadian rhythm, which proves very beneficial in a wide assortment of conditions.

Patients also buy Agomelatine over other antidepressants for its other benefits:

• It works faster than other antidepressants, with improvements often seen within the first week.
• It's more effective in nearly all cases, with greater improvement and fewer relapses.
• It's better tolerated, with no sexual side effects or weight gain.
• It's easy to administer; a single dose at bedtime.
• It produces no withdrawal symptoms when treatment ends, even abruptly.
• It's non-addictive.

Other antidepressants, though often beneficial as well, can take several months before producing significant benefit, and many patients stop using them due to side effects or difficult dosing schedules. In trials, very few patients stopped taking Agomelatine.

What to Expect from Agomelatine

Before buying Agomelatine, regardless of what it's to be used for, patients should have liver function tested. Individuals with moderate to severe liver damage are poor candidates for this medication; patients with normal to low liver function will need to have their liver function monitored periodically throughout treatment, typically every 3, 6, 12 and 24 weeks after starting treatment. This can be a hassle, but is preferable to liver damage.

Patients buying Agomelatine for the first time will want to start on 25 mg doses. Some individuals find 25 mg is not enough; these patients will likely be instructed to take two 25 mg tablets, for a total daily dose of 50 mg.

Tablets should be taken at bedtime, just once per day, regardless of dosage. Food is optional.

Treatment typically consists of:

• Take one dose at bedtime every day.
• If a dose is forgotten, it should be skipped entirely.
• Treatment should continue for at least 6 months after symptoms are resolved.
• Standard treatment is 9 months.
• Treatment can end abruptly; there are no withdrawal effects.

Improvements are usually seen within a week of starting treatment, but it may take two weeks to a month for full benefit to be seen. Provided no adverse effects develop, continue taking Agomelatine for at least a month; if no improvement is seen after a month, alternative treatments should be considered.

Before Buying Agomelatine

Though a very effective medication with few of the side effects associated with other antidepressants, Agomelatine is not without risks. As mentioned above, liver damage is a great concern. Risk of liver damage increases with duration of use; this medication should not be used for longer than 9 months without explicit doctor approval and commitment to regular liver screenings.

Patients who may require modified dosing and increased monitoring include those who:

• Are under age 25 or over age 65
• Have a history of kidney problems
• Are obese
• Have diabetes
• Consume large volumes of alcohol or recreational drugs
• Have a history of bipolar disorder, mania, or hypomania
• Take medications that influence levels of the CYP1A2 enzyme or rely on CYP1A2 for metabolism.

Otherwise healthy patients are unlikely to experience serious side effects. Most common include:

• Nausea or vomiting
• Abnormal dreams
• Drowsiness
• Dizziness
• Back pain
• Diarrhea or constipation

The above are not cause for concern unless severe or persistant.

Help is just a Click Away

Kiwi Drug is happy to offer this effective antidepressant to our clients around the globe. Clients who buy Agomelatine from Kiwi Drug will also receive peace of mind knowing their order is in the competent hands of New Zealand's oldest and most-trusted online pharmacy---we are subject to the same regulatory compliance as our real-world counterparts and backed by an international network of brick & mortar pharmacies to ensure your medications are safe and authentic.

A prescription is needed to buy Agomelatine from Kiwi Drug; if you don't have one you may want to take advantage of our online doctor services:

• Add the product to your cart and initiate checkout.
• Answer the questions on the following page about your medical history and other medications being taken.
• There is no extra charge for our online doctor services.

Patients who already have a prescription to buy Agomelatine will be given options to transfer it to us upon completing checkout.

As always, we're standing by to help if you have any questions or need a hand with your order.